2-Bromopalmitic acid

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SKU:
10-3284-500mg
Availability:
Y
126$
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Description

SKU:
10-3284-500mg
Additional Names:
2-BP
CAS Number:
18263-25-7
Extra Details:
Inhibits protein S-palmitoylation.1 Blocks palmitic acid-induced increase in cAMP levels in human primary melanocytes expressing the melanocortin-1 receptor which undergoes an essential palmitoylation as a prerequisite for receptor signaling.2
Molecular Weight:
335.23
Physical State:
White solid
References:
1) Tsukamoto et al. (2013), Role of S-palmitoylation on IFITM5 for the interaction with FKBP11 in osteoblast cells; PLoS One, 8(9) e75831 2) Chen et al. (2017), Palmitoylation-dependent activation of MC1R prevents melanomagenesis; Nature, 549 399
Shipping Conditions:
Ambient
Storage Conditions:
Room Temperature
Supplier:
Focus Biomolecules
  • Manufacturer's Data Sheet:
Purity:
98% by TLC, NMR (Conforms)
Chemical Name:
2-Bromohexadecanoic acid (racemic)
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