Description
- SKU:
- SMC-511D-HRP
- Additional Names:
- 4-Hydroxynonenal Antibody, 4-Hydroxy Nonenal (4-HNE) Antibody, 4-Hydroxy Nonenal Antibody, 4-HNE Antibody, 4-hydroxy Hexenal Antibody, HNE Antibody, 4-hydroxy-2-nonenal Antibody
- Application:
- ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Clone:
- 12F7
- Clonality:
- Monoclonal
- Conjugate:
- HRP
- Concentration:
- 1 mg/ml
- Extra Details:
- 4-Hydroxy-2-nonenol (4-HNE) is an unsaturated aldehyde derived from lipid peroxidation. 4-HNE is an electrophile and reacts with protein nucleophiles such as cysteine, histine, and lysine (1). Low levels of 4-HNE promote cell survival via cellular antioxidant induction whereas higher levels lead to autophagy, apoptosis, and ultimately necrosis. 4-HNE has been linked to Alzheimer's disease, Parkinson's disease, cancer, cardiovascular diseases, diabetes, and liver disease.
- Host:
- Mouse
- Immunogen:
- Synthetic 4-Hydroxynonenal modified Keyhole Limpet Hemocyanin (KLH).
- Isotype:
- IgG1
- Purification:
- Protein G Purified
- Reactivities:
- Wide/Non-species Specific
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Monoclonal Antibody
- Size:
- 100 ug
- Specificity:
- Specific for 4-HNE modified proteins. Does not detect free 4-Hydroxynonenal. Does not X-react with 4-HHE, Acrolein, Crotonaldehyde, Hexanoyl Lysine, MDA, or Methylglyoxal modified proteins.
- Preservative:
- 0.09% Sodium azide
- Long Description:
- Mouse Anti-4-Hydroxynonenal (4-HNE) Monoclonal IgG1
