Description
- SKU:
- SPC-1339D-A488
- Additional Names:
- eIF4E-binding protein 1 Antibody, 4E-BP1 Antibody, Phosphorylated heat- and acid-stable protein regulated by insulin 1 Antibody, Eukaryotic translation initiation factor 4E-binding protein 1 Antibody, PHAS-I Antibody, EIF4EBP1 Antibody
- Application:
- Immunohistochemistry, Western Blot
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Clonality:
- Polyclonal
- Conjugate:
- ATTO 488
- Extra Details:
- 4E-BP1 binds to eIF4E, preventing its assembly into the EIF4F complex and inhibiting cap-dependent translation. Phosphorylation of 4E-BP1 disrupts this binding, activating cap-dependent translation.
- Gene Details:
- EIF4EBP1
- Host:
- Rabbit
- Immunogen:
- Synthetic phospho-peptide from human 4E-BP1 around the phosphorylation site of threonine 45 (pThr45).
- Isotype:
- IgG
- Protein Details:
- Q13541
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Polyclonal Antibody
- Size:
- 100 ul
- Specificity:
- Detects endogenous levels of 4E-BP1 only when phosphorylated at threonine 45 (pThr45). Detects a band at ~18 kDa.
- Post Translational Modification:
- Phosphorylated
- Preservative:
- 0.02% Sodium azide
- Long Description:
- Rabbit Anti-Human 4E-BP1 (pThr45) Polyclonal
- Accession:
- NP_004086.1
- Synonyms:
- 4EBP1;4E-BP1;BP-1;eIF4E-binding protein 1;eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I;phosphorylated heat- and acid-stable protein regulated by insulin 1