Description
- SKU:
- 10-2053-5mg
- CAS Number:
- 7240-37-1
- Extra Details:
- Fluorescent, intercalating DNA-binding agent useful for identifying apoptotic cells by flow cytometry.1,2 Capable of identifying populations representing live, apoptotic, and late apoptotic/dead cells in a quick, simple, reproducible, cost-effective fashion.3,4 Inhibitor of DNA-primed RNA polymerase and DNA polymerase.5
- Molecular Weight:
- 1270.42
- Physical State:
- purple solid
- References:
- 1) Telieps et al. (2013) Cellular-FLIP, Raji isoform (c-FLIP R) modulates cell death induction upon T-cell activation and infection, Eur.J.Immunol. 43 1499 2) Schmid et al. (2007) Live-cell assay for detection of apoptosis by dual-laser flow cytometry using Hoechst 33342 and 7-amino-actinomycin D, Nat.Protoc. 2 187 3) Toba et al. (2000) Cell kinetic study of normal human bone marrow hematopoiesis and acute leukemia using 7AAD/PY, Eur.J.Haematol. 64 10 4) Lecoeur et al. (1997) Strategies for phenotyping apoptotic peripheral human lymphocytes comparing ISNT, annexin-V and 7-AAD cytofluorometric staining methods, J.Immunol.Methods 209 111 5) Su et al. (1996) Hematopoietic cell protein-tyrosine phosphatase-deficient motheaten mice exhibit T cell apoptosis defect, J.Immunol. 156 4198
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20°C
- Supplier:
- Focus Biomolecules
- Purity:
- 98% by HPLC NMR (conforms)