Description
- SKU:
- PP-160
- Additional Names:
- TAT-TRPV1(736-745)
- Extra Details:
- 736-745-TAT, also known as TAT-TRPV1(736-745), is a cell permeable TRPV1 fragment that can inhibit the interaction of TRPV1 and AKAP79. 736-745-TAT consists of amino acids 736-749 from the TRPV1 C-terminal domain, combined with amino acids 47-57 of TAT to promote uptake across neuronal cell membranes. 736-745-TAT inhibits both the first and the second phase of pain behaviour in the formalin test, implying an effect on both acute and inflammatory pain.
- Molecular Weight:
- 2929.41
- Purity:
- >95% by HPLC
- References:
- Fischer et al (2013) Disrupting sensitization of transient receptor potential vanilloid subtype 1 inhibits inflammatory hyperalgesia. J. Neurosci. 33(17) 7407 doi:10.1523/JNEUROSCI.3721-12.2013
- Sequence:
- H-Lys-Asp-Asp-Tyr-Arg-Trp-Cys-Phe-Arg-Val-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg- Arg-OH
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Supplier:
- Isca Biochemicals
- Formula:
- C127H206N50O29S1
- Solubility:
- Soluble in DMSO
