Description
- SKU:
- 10-4535-250mg
- Additional Names:
- 2-PCPA, SKF-385
- CAS Number:
- 13492-01-8
- Extra Details:
- Tranylcypromine is an irreversible and non-selective monoamine oxidase inhibitor.1,2 It has been shown to inhibit the histone demethylase BHC110/LSD1.3,4
- Molecular Weight:
- 182.23
- Physical State:
- White solid
- References:
- 1) Knoll et al. (1980), Monoamine oxidase inhibitors: Chemistry and Pharmacology; In, Sandler (ed) Enzyme inhibtors as drugs, MacMillan, London 151 2) Baker et al. (1992), Insights into the mechanisms of action of the MAO inhibitors phenelzine and tranylcypromine; a review, J.Psychiatry Neurosci. 17 206 3) Lee et al. (2006), Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications; Chemistry and Biology, 13 563 4) Schmidt and McCafferty (2007), trans-2-Phenylcyclopropylamine is a Mechanism-Based Inactivator of the Histone Demethylase LSD1 Biochemistry 46 4408
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20°C
- Supplier:
- Focus Biomolecules
- Purity:
- 98% by TLC, NMR (Conforms)
- Chemical Name:
- trans-(±)-2-Phenylcyclopropylamine hemisulfate