Description
- SKU:
- L-5216
- Additional Names:
- 16:0 LPG, 326495-22-1, Lyso PG
- Extra Details:
- 1-palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 LPG) is a form of lysophosphatidylglycerol (LPG), which increases intracellular Ca2+ release and induces phosphorylation on ERK and Akt in OVCAR3 cells however the exact receptor has not been identified. LPG can also modulate the formyl peptide like-1 activated inflammatory response in human phagocytes. Lysophospholipids are lipid mediators which elicit a diverse array of cellular responses through activation of phospholipid specific G protein-coupled receptors.
Storage
-20 °C or belowReferences
1). K. Makide, et al “Novel lysophosphoplipid receptors: their structure and function” Journal of Lipid Research, 2014, 55, 1986; 2) J.W. Shim, et al. “Lysophosphatidylglycerol inhibits formyl peptide receptor like-1-stimulated chemotactic migration and IL-1? production from human phagocytes” Exp. Mol. Med., 2009, 41, 584-591. 3) K.S Park, et al. “Effect of lysophosphatidylglycerol on several signaling molecules in OVCAR-3 human ovarian cancer cells: involvement of pertussis toxin-sensitive G-protein coupled receptor.” Biochem. Pharmacol., 2007, 73, 675-81.
Documents
Technical Data Sheet - Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Echelon Biosciences
