Description
- SKU:
- SMC-536D-PCP
- Additional Names:
- 4-Hydroxy-2-hexenal (4-HHE) Antibody, 4-Hydroxy-2-hexenal Antibody, 4-HHE Antibody, MG Antibody, MG-modified protein Antibody, 4-Hydroxy-2-hexenal-modified , 4-Hydroxy-2-hexenal Antibody, 4-hydroxy Hexenal Antibody, HHE Antibody, 4-HHE Antibody
- Application:
- ELISA, Western Blot
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Clone:
- 5C11.1
- Clonality:
- Monoclonal
- Conjugate:
- PerCP
- Concentration:
- 1 mg/ml
- Extra Details:
- Lipid peroxidation occurs when oxidizing agents attack carbon-carbon double bonds found in unsaturated lipids. In addition to membrane degradation, oxidation end-products have been found to damage cell viability through their mutagenic and toxic properties. These downstream functional consequences facilitate the development of disease and premature aging. 4-hydroxy-2-hexenal (4-HHE) is a major alpha,beta-unsaturated aldehyde product of n-3 PUFA oxidation resulting from lipid peroxidation. High levels of HHE are found in disease states (1). 4-HHE reacts with histidine residues to form Michael-addition type adducts.
- Host:
- Mouse
- Immunogen:
- Synthetic 4-Hydroxy-2-hexenal modified Keyhole Limpet Hemocyanin (KLH)
- Isotype:
- IgG1
- Purification:
- Protein G Purified
- Reactivities:
- Wide/Non-species Specific
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Monoclonal Antibody
- Size:
- 100 ug
- Specificity:
- Specific for 4-HHE. Slight cross-reactivity with 4-Hydroxynonenal. Does not cross-react with Acrolein, Crotonaldehyde, Hexanoyl Lysine, MDA, or Methylglyoxal modified proteins.
- Preservative:
- 0.09% Sodium azide
- Long Description:
- Mouse Anti-4-Hydroxy-2-hexenal Monoclonal IgG1
