Description
- SKU:
- 10-3700-100ug
- CAS Number:
- 13072-89-4
- Extra Details:
- 4,9-Anhydrotetrodotoxin is a highly selective blocker of the Na(v1.6) sodium channel. (IC50s: Na(v1.2) = 260 nM, Na(v1.3) = 341 nM, Na(v1.4) = 988 nM, Na(v1.5) = 11.6 µM, Na(v1.6) = 7.8 nM, Na(v1.7) = 1.27 µM, Na(v1.8) = >30 µM.).1
- Molecular Weight:
- 301.25
- Physical State:
- Colorless film
- References:
- 1) Rosker et al. (2007), The TTX metabolite 4,9-anhydro-TTX is a highly specific blocker of the Na(v1.6) voltage-dependent sodium channel; Am.J.Physiol.Cell Physiol., 293 C783.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20°C
- Supplier:
- Focus Biomolecules
- Purity:
- >98% by HPLC : [1% acetonitrile / 0.05M NH4OAc, 0.5 ml/min, Luna C18, ELSD detection], NMR: Conforms High Res Mass: Conforms