Description
- SKU:
- SIH-423-5MG
- Additional Names:
- 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide, A-83-01, A83-01
- CAS Number:
- 909910-43-6
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- A83-01 is a selective inhibitor of TGF-B Beta type I receptor ALK5 kinase. It blocks phosphorylation of Smad2 and inhibits TGF-B Beta-induced epithelial-to-mesenchymal transition. A 83-01 also inhibits the transcriptional activity induced by TGFB Beta type I receptor ALK-5, activin type IB receptor ALK-4 and nodal type I receptor ALK-7.
- Molecular Weight:
- 421.5
- Purity:
- ?98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecoles & Other Biomolecules: Inhibitors
- Size:
- 5 mg
- Long Description:
- ALK kinase inhibitor
