Description
useful for research of potencial role of AGEs modification in nomal ging as well as age-enhanced disease processes [Concentration: 1 mg / ml
The products of the nonenzymatic glycation and oxidation of proteins, lipids and nucleic acids, the advanced glycation end-products (AGEs), accumulate in various pathological conditions, such as diabetes,inflammation, renal failure, and aging. AGEs accumulate at site of microvascular injury in diabetes, including the kidney, the retina, and within the vasculature. The enhanced formation of AGEs also exists in various disease, such as atherosclerosis,Alzheimer's disease, end-stage renal disease (ESRD), rheumatoid arthritis and liver cirrhosis. AGEs can arise not only from glucose, but also from dicarbonyl compounds, short chain-reducing sugars and other metabolic pathways of glucose. This was prepared from D-glucose and BSA.
View AllClose
The products of the nonenzymatic glycation and oxidation of proteins, lipids and nucleic acids, the advanced glycation end-products (AGEs), accumulate in various pathological conditions, such as diabetes,inflammation, renal failure, and aging. AGEs accumulate at site of microvascular injury in diabetes, including the kidney, the retina, and within the vasculature. The enhanced formation of AGEs also exists in various disease, such as atherosclerosis,Alzheimer's disease, end-stage renal disease (ESRD), rheumatoid arthritis and liver cirrhosis. AGEs can arise not only from glucose, but also from dicarbonyl compounds, short chain-reducing sugars and other metabolic pathways of glucose. This was prepared from D-glucose and BSA.
