Description
Clonality: Monoclonal
Host: Mouse
Purification: Ascities
Reactivity: Drosophila
Ca2+/calmodulin-dependent protein kinase II (CaM kinase II or CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+/calmodulin complex. CaMKII is involved in many signaling cascades and is thought to be an important mediator of learning and memory.[1] CaMKII is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes,[2] chloride transport in epithelia,[3] positive T-cell selection,[4] and CD8 T-cell activation.[5] Misregulation of CaMKII is linked to Alzheimer’s disease, Angelman syndrome, and heart arrhythmia.[6] [from: Wikipedia contributors. (2019, March 15). Ca2+/calmodulin-dependent protein kinase II. In Wikipedia, The Free Encyclopedia. Retrieved 20:14, June 4, 2019, from https://en.wikipedia.org/w/index.php?title=Ca2%2B/calmodulin-dependent_protein_kinase_II&oldid=887834881]
References:
Takamatsu Y, Kishimoto Y and Ohsako S. (2003) Immunohistochemical study of Ca2+/calmodulin-dependent protein kinase II in the Drosophila brain using a specific monoclonal antibody. Brain Res. 974:99-116.
