Description
Application: ICC, WB, ELISA
Clonality: Monoclonal
Host: Rat
Purification: Ion-exchange Chromatography
Reactivity: Monkey, Mouse, Rat, Human, Hamster
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Clonality: Monoclonal
Host: Rat
Purification: Ion-exchange Chromatography
Reactivity: Monkey, Mouse, Rat, Human, Hamster
Post-translation modifications of histones modulate the accessibility and transcriptional competence of specific chromatin regions within the eukaryotic genome. Phosphorylation of histone H3 is unique in the sense that it associates on one hand with open chromatin during gene activation and marks on the other hand highly condensed chromatin during mitosis.
References:
1) Strahl and Allis, (2000) Nature. 403(6765):41-5. PMID: 10638745
