Description
Application: ICC, WB, ELISA
Clonality: Monoclonal
Host: Rat
Purification: Ion-exchange Chromatography
Reactivity: Hamster, Monkey, Mouse, Rat, Human
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Clonality: Monoclonal
Host: Rat
Purification: Ion-exchange Chromatography
Reactivity: Hamster, Monkey, Mouse, Rat, Human
Post-translation modifications of histones modulate the accessibility and transcriptional competence of specific chromatin regions within the eukaryotic genome. Phosphorylation of histone H3 Threonine 11 (H3-T11ph) occurs throughout the cell cycle and is Chk1 dependent. It has been reported that DNA damage rapidly reduces H3-T11 phosphorylation.
References:
Shimada M, et al. (2008) Cell. 132(2):221-32. PMID: 18243098.
