Anti Proprotein Convertase Subtilisin/Kexin Type 6 (PACE4) - HomoB domain pAb (Rabbit, Antiserum)

PACE4 is a member of the processing protease family that controls cell differentiation and morphogenesis. Its structure and function have been elucidated by Professor Akihiko Tsujij's research group at Tokushima University. PACE4 is believed to play a particularly important role in development and differentiation processes such as organogenesis. In recent years, it has been suggested that it is involved in cancer metastasis and activation of matrix metalloproteinases.

Source: Professor Akihiko Tsuji, Faculty of Engineering, Tokushima University

References:
1) Nagahama et al. (1998) Biosynthetic processing and quaternary interaction of proprotein convertase SPC4
(PACE4). FEBS Letters 434, 155-159.
2) Tsuji et al. (2003) Secretory proprotein convertases PACE4 and PC6A are heparin-binding proteins which are localized in the extracellular matrix. Biochim. Biophys. Acta 1645, 95-104.