Description
Application: ICC, IHC, WB, IF
Clonality: Monoclonal
Host: Mouse
Purification: IgG
Reactivity: Mouse, Human
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Clonality: Monoclonal
Host: Mouse
Purification: IgG
Reactivity: Mouse, Human
SMARCB1/INI1/BAF47 is a core component of the BAF (SWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal.
References:
1) Hollmann and Hornick (2011) Am J Surg.