Anti Transcription Activator BRG1 (SMARCA4) mAb (Clone 5B7)

Brm-related gene-1 (Brg1) is a catalytic subunit of the SWI/SNF chromatin remodeling enzyme complex that has ATPase activity. This complex facilitates chromatin remodeling for gene expression by utilizing energy from ATP hydrolysis. It is well known that the SWI/SNF chromatin remodeling enzyme complex is essential for cell differentiation, cell cycle regulation, and embryogenesis.

References:
1) Ohkawa et al. (2007) J. Biol. Chem. 282:6564-6570.
2) Ohkawa et al. (2010) Hybridoma. 6:463-466.