Description
Application: IF, WB, ICC
Clonality: Polyclonal
Host: Rabbit
Purification: Serum
Reactivity: Hamster, Human, Mouse, Rat
TAFIID subunit1 (1,872 aa, 213 kDa) is the largest component and core scaffold of the TFIID basal
transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can
autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to
MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses
DNA-binding activity. Essential for progression of the G1 phase of thecell cycle. Application: 1) Western blotting (1/1,000 dilution)
2) Immunofluorescent staining (1/1,000~1/5,000)
Other applications have not been tested
Cross reactivity: Human, hamster, mouse and rat. Not tested in otherspecies
Immunogen: Synthetic peptide of human TFIID subunit 1 protein corresponding to amino acids 103-123,
STEDAVDYSDINEVAEDESRR-C , conjugated with KLH
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Clonality: Polyclonal
Host: Rabbit
Purification: Serum
Reactivity: Hamster, Human, Mouse, Rat
TAFIID subunit1 (1,872 aa, 213 kDa) is the largest component and core scaffold of the TFIID basal
transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can
autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to
MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses
DNA-binding activity. Essential for progression of the G1 phase of thecell cycle. Application: 1) Western blotting (1/1,000 dilution)
2) Immunofluorescent staining (1/1,000~1/5,000)
Other applications have not been tested
Cross reactivity: Human, hamster, mouse and rat. Not tested in otherspecies
Immunogen: Synthetic peptide of human TFIID subunit 1 protein corresponding to amino acids 103-123,
STEDAVDYSDINEVAEDESRR-C , conjugated with KLH
