SHEEP ANTI-EBOLA VIRUS

The Native Antigen Company Sheep anti Ebola virus antibody has been raised against recombinant EBOV virus like particles (VLPs), expressed in mammalian cells. These VLPs are comprised of EBOV Nucleoprotein (NP), glycoprotein (GP) and the VP40 protein. The antibody has been shown to react with each of the components of the VLP in Western blotting analysis, when used at a 1/2,500 dilution.

PRODUCT DETAILS – SHEEP ANTI-EBOLA VIRUS

• Sheep anti-Ebola virus polyclonal IgG antibody.
• Buffered in PBS, pH7.4.

BACKGROUND

Ebola virus is a member of the filovirus family which are single-stranded negative sense RNA viruses. Virions are mainly composed of the matrix protein VP40, the nucleoprotein NP which encases the viral nucleic acid, and the glycoprotein GP. Members of this family include Zaire, Sudan and Reston Ebola viruses and Marburg virus.

The Zaire subtype of the Ebola virus family is currently the most important in relation to outbreaks of disease in humans. This subtype has been responsible for the largest ever outbreak of EHF, which started in West Africa in 2014, and was finally declared over only in early 2016. The Boende-Lokolia strain was identified at the beginning of this outbreak in the villages of Boende and Lokolia in the Democratic Republic of Congo. No effective treatments or vaccines have been approved by any governing body as of 2017.