Description
- SKU:
- AM-120
- Additional Names:
- Nonaarginine, Nona-L-arginine, Peptide R9
- CAS Number:
- 143413-47-2
- Extra Details:
- (Arg)9, also known as nonaarginine, is a a cationic cell penetrating peptide (CPP) consisting of 9 arginines. Arginine-rich cell-penetrating peptides including (arg)9 do not enter cells by directly passing through a lipid membrane but instead passively enter vesicles and live cells by inducing membrane multilamellarity and fusion. (Arg)9 also possesses antifungal and neuroprotective properties.
- Molecular Weight:
- 1423.7
- Purity:
- >95% by HPLC
- References:
Holm et al (2012) Cell-penetrating peptides as antifungals towards Malassezia sympodialis. Lett. Appl. Microbiol. 54 39 PMID: 22023266
Milani et al (2016) Poly-arginine peptides reduce infarct volume in a permanent middle cerebral artery rat stroke model. BMC Neurosci. 17(1) 19 doi:10.1186/s12868-016-0253-z
Allolio et al (2018) Arginine-rich cell-penetrating peptides induce membrane multilamellarity and subsequently enter via formation of a fusion pore. Proc. Natl. Acad. Sci. 115 (47) 11923 PMID: 30397112
- Sequence:
- H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store frozen and desiccated in the dark
- Supplier:
- Isca Biochemicals
- Formula:
- C54H110N36O10
- Solubility:
- Soluble in dilute acid
