CARD HyperOva® (Superovulation Reagent for mouse)

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CARD HyperOva^® (Superovulation Reagent for mouse) (Japanese Patent No. 5927588) is an ultra-superovulation reagent that is 3-4 times more efficient at inducing ovulation than the conventional PMSG-hCG method (80 ova per C57BL/6 mouse versus approximately 20). CARD HyperOva^® is also effective with many other strains. Even further gains in efficiency can be realized by using CARD MEDIUM^® during the IVF procedure.

Why Use CARD HyperOva^®?

• Reduce Animal Use (contribute to the 3Rs of animal welfare: Replacement, Reduction, Refinement)
• Using CARD HyperOva^® can reduce the number of oocyte donor mice by a factor of 1/3-1/4.
• Optimize creation and preservation of genetically modified mice.
• More ova from fewer mice using CARD HyperOva^® facilitates in vitro fertilization and embryo transfer.
• More ova from fewer mice using CARD HyperOva^® enables the large-scale preparation of embryos.
• Get more done!

For information on techniques for mouse spermatozoa cryopreservation, spermatozoa thawing, in vitro fertilization and obtaining pups through embryo transfer, please refer to the CARD website: http://card.medic.kumamoto-u.ac.jp/card/english/sigen/index.html