Description
[Application]
The immunological study in HBV and the research of the infection mechanismHepatitis B virus (HBV) expresses three types of surface antigens, i.e. S-, M-, and L-protein. L-protein is composed of S-, Pre-S2, and Pre-S1 region. The deletion of Pre-S1 region forms M-protein, and further deletion of Pre-S2 regionresults in S-protein. Most of commercially available HBsAgs is composed of either S-protein alone or S- plus M-proteins. This product, HBsAg, L-protein contains all the three components in one protein. The Pre-S1 region is known to be the hepatic cell recognition site and to be important in the HBV infection. Thus, the product can be used as a mimic HBV for immunological studies or as a tool for studying infection mechanism.
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The immunological study in HBV and the research of the infection mechanismHepatitis B virus (HBV) expresses three types of surface antigens, i.e. S-, M-, and L-protein. L-protein is composed of S-, Pre-S2, and Pre-S1 region. The deletion of Pre-S1 region forms M-protein, and further deletion of Pre-S2 regionresults in S-protein. Most of commercially available HBsAgs is composed of either S-protein alone or S- plus M-proteins. This product, HBsAg, L-protein contains all the three components in one protein. The Pre-S1 region is known to be the hepatic cell recognition site and to be important in the HBV infection. Thus, the product can be used as a mimic HBV for immunological studies or as a tool for studying infection mechanism.