Description
Applications: Mitogen for epithelial cells
Western blot control for anti-FGF-7 antibodies
Acceleration of wound healing is implied.
Acceleration of hair development is implied. Keratinocyte Growth Factor (KGF), also known as Fibroblast Growth Factor 7 (FGF-7), is a member of fibroblast growth factor (FGF) family. Although FGF-7 has heparin binding activity similar to FGF-> its mitogenic activity is predominantly exhibited in keratinocytes. It is not effective to fibroblasts and endothelial cells.
The human FGF-7 lacking the signal sequence (1-31 aa) was expressed in E. coli and purified by the chromatographic procedures. This product is an intact enzymewithout tag with 19 kDa size (Fig.).
Measurement of the activity: The ED50 as determined by a cell proliferation assay using MTS assay kit (CellTiter 96, Promega) with human keratinocyte JCRB141cells was <10 ng / ml .
GeneID: 2252
GeneSequence: M60828.1
Amino Acid Sequence: P21781
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Western blot control for anti-FGF-7 antibodies
Acceleration of wound healing is implied.
Acceleration of hair development is implied. Keratinocyte Growth Factor (KGF), also known as Fibroblast Growth Factor 7 (FGF-7), is a member of fibroblast growth factor (FGF) family. Although FGF-7 has heparin binding activity similar to FGF-> its mitogenic activity is predominantly exhibited in keratinocytes. It is not effective to fibroblasts and endothelial cells.
The human FGF-7 lacking the signal sequence (1-31 aa) was expressed in E. coli and purified by the chromatographic procedures. This product is an intact enzymewithout tag with 19 kDa size (Fig.).
Measurement of the activity: The ED50 as determined by a cell proliferation assay using MTS assay kit (CellTiter 96, Promega) with human keratinocyte JCRB141cells was <10 ng / ml .
GeneID: 2252
GeneSequence: M60828.1
Amino Acid Sequence: P21781
