LipoTrust PE

For gene / nucleic acid transfectionThis is cationic liposome which consists of three highly effective transfection formulations strictly selected from more than three hundreds. What makes them unique is that no conversion to serum-free medium is required at the transfection. And they show high gene expression activity both in vitro and in vivo.

LipoTrust™ SR : shows high gene expression activity to many kinds of cells in the presence of serum

LipoTrust™ PE : shows constant gene expression activity in the presence or absence of serum

LipoTrust™ CH : shows remarkably high gene expression activity in the serum-free medium, and is available for transfection into non-adherent type cells.

As most transfection reagents have little gene expression activity in serum-containing medium, use of serum-free medium is recommended. LipoTrust™ has enough gene expression activity in serum-containing medium as well, so that it can be used in both type of experiments with or without serum either in vitro or in vivo.

Though general transfection reagents are known to be cytotoxic, LipoTrust™ causes much less cytotoxicity. Moreover, the product form, lyophilizate, makes it possible to choose from two types depend on your purpose. Oneis Coating Type, which is to be used by dissolving the empty LipoTrust™ with nucleic acid solution to reconstruct liposomal membrane without compromising effective nucleic acid retention. The other Lipoplex Type is the general type which is used by mixing the transfection reagent solution with nucleic acid solution.