NEUROBIOTIN[R]-PLUS Tracer

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SKU:

SP-1150-5

Availability:

Description

Description

SKU:

SP-1150-5

Additional Names:

Specialty Products [Neuronal Tracers ], Anterograde , Retrograde

Conjugate:

Biotin

Extra Details:

NEUROBIOTIN[TM]-Plus Tracer is impervious to cleavage and breakdown by biotinidase. Investigators have identified rapid degradation of injected tracers such as biocytin due to the presence of biotinidase activity in brain tissue*. This loss of stability of the tracer significantly reduces the viable postinjection period and may compromise complete detection of a neural network. NEUROBIOTIN[TM] -Plus was designed to be impervious to cleavage and breakdown by biotinidase. This newly synthesized biotin-containing compound contains fixable amine groups, is highly soluble and has a low molecular weight. These characteristics make it an ideal candidate for experiments requiring long postinjection survival times and optimal uptake along the entire neural tract.

NEUROBIOTIN[TM] -Plus shares the same key advantages of NEUROBIOTIN[TM] Tracer over biocytin and other neuronal labels:

Better solubility

More efficiently iontophoresed

Remains in cell longer

Non-toxic

Can be fixed with formalin or glutaraldehyde

NEUROBIOTIN[TM] -Plus can be detected using avidin or streptavidin systems with either chromogenic or fluorescence visualization methods.

Molecular Weight:

358

Research Area:

Neuroscience

Shipping Conditions:

Ambient

Storage Conditions:

2-8 [o]C (desiccated). Once in solution, store frozen. This product does not contain an antimicrobial agent.

Supplier:

Vector Laboratories

Size:

5mg

Manufacturer's Data Sheet:neurobiotin-plus.html