Peanut Agglutinin (PNA), Unconjugated

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Description

SKU:: L-1070-25
Additional Names:: Lectins & Glycobiology Reagents [Lectins ], Arachis hypogaea lectin, galactosyl (beta 1;3) N-acetylgalactosamine
Application:: Immunohistochemistry, IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Immunofluorescence
Extra Details:: Peanut agglutinin binds preferentially to the T-antigen, a galactosyl (?-1,3) N-acetylgalactosamine structure present in many glycoconjugates such as M and N blood groups, gangliosides, and many other soluble and membrane-associated glycoproteins and glycolipids. With certain exceptions, the receptor sequence for PNA is normally sialylated which prevents the lectin from binding to its receptor oligosaccharide (see Jacalin). Even sialic acid which is not bound directly to the receptor sugars may inhibit binding. The presence of calcium ions in diluents can enhance the binding of PNA to receptors, possibly by neutralizing the negative charges on sialic acid residues adjacent to the receptor sequence.
Purification:: Affinity Purified
Research Area:: Glycobiology
Shipping Conditions:: Ambient
Storage Conditions:: 2-8 [o]C
Supplier:: Vector Laboratories
Size:: 25mg