Recombinant Hepatitis B virus (HBV) Large Envelope Protein S Domain with high antigenic activity (HBsAg-XT)

Hepatitis B virus surface antigen (HBsAg) is composed of L-, M- and S-antigen. Among them S-antigen activity is known to be the major antigen of human derived HBsAg. This product, HBsAg-XT, is specifically designed to exhibit high S antigen activity and produced from yeast. Using ELISA analysis to detect S-antigen activity, the product showed almost equal antigen activity to that of partially purified HBsAg derived from HVB patients. The antigen resembles in structure with that ofHBsAg derived from HBV patients, but is free from potential HBV infections, and thus can be used not only as a S-antigen but also as mimic HBsAg.