Description
- SKU:
- 10-2508-250mg
- Additional Names:
- ABT, 1-Benzotriazolylamine, NSC-114498
- CAS Number:
- 1614-12-6
- Extra Details:
- A pan-specific cytochrome P450 inhibitor acting as a suicide substrate.1,2 Blocks omega-oxidation of arachidonic acid but not its epoxidation.3 A pan-specific cytochrome P450 inhibitor acting as a suicide substrate.1,2 Blocks omega-oxidation of arachidonic acid but not its epoxidation.3
- Molecular Weight:
- 134.14
- Physical State:
- Off-white solid
- References:
- 1) Mugford et al. (1995), 1-Aminobenzotriazole-Induced Destruction of Hepatic and Renal Cytochrome P450 in Male Sprague-Dawley Rats; Fundam. Appl. Tox., 19 43 2) Emoto et al. (2005), In Vitro Inhibitory Effect of 1-Aminobenzotriazole on Drug Oxidations in Human Liver Microsomes: A Comparison With SKF-525A; Drug Metab. Pharmacokinet., 20 351 3) Su et al. (1998), Inhibition of Renal Arachidonic Acid Omega-Hydroxylase Activity With ABT Reduces Blood Pressure in the SHR; Am. J. Physiol., 275 R426
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20°C
- Supplier:
- Focus Biomolecules
- Purity:
- 98% by HPLC NMR (Conforms)
