Description
- SKU:
- 10-1330-1mg
- CAS Number:
- 77058-74-3
- Extra Details:
- Cholesterol metabolite. Endogenous agonist for nuclear receptor LXR1. Controls cellular cholesterol homeostasis2. Promotes neural development in zebra fish as well as dopaminergic differentiation of embryonic stem cells3. Cell permeable.
- Molecular Weight:
- 400.65
- Physical State:
- White solid
- References:
- 1) Chawla et al. (2001), Nuclear receptors and lipid physiology: opening the X-files; Science, 294 1866 2) Brown et al. (2009), 24(S),25-epoxycholesterol: a messenger for cholesterol homeostasis; Int. J. Biochem. Cell Biol., 41 744 3) Theofilopoulos et al. (2013), Brain endogenous liver X receptor igands selectively promote midbrain neurogenesis; Nature Chem. Biol., 9 126
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20°C
- Supplier:
- Focus Biomolecules
- Purity:
- 98% by TLC, NMR (Conforms)