Lens Culinaris Agglutinin (LCA), DyLight[R] 649

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SKU:
DL-1048-1
Availability:
Y
207$
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Description

SKU:
DL-1048-1
Additional Names:
Lectins & Glycobiology Reagents [Lectins ], Lentil Lectin, Mannose binding Lectin
Application:
Immunofluorescence
Conjugate:
DyLight 649
Extra Details:
LCA recognizes sequences containing ?-linked mannose residues but recognizes additional sugars as part of the receptor structure, giving it a narrower specificity than Con A. An ?-linked fucose residue attached to the N-acetylchitobiose portion of the core oligosaccharide significantly enhances affinity. By exploiting this narrower specificity, glycoproteins and glycopeptides can be subfractionated with LCA after initial isolation with Con A. DyLight[R] 649 labeled LCA has an appropriate number of fluorochromes bound to provide the optimum staining characteristics for this lectin. This conjugate is supplied essentially free of unconjugated fluorochromes. Excitation maximum: 655 nm Emission maximum: 670 nm Color: Far red

Lens culinaris agglutinin is composed of four subunits - two of about 17kDa and two of 8kDa. LCA recognizes sequences containing ?-linked mannose residues but recognizes additional sugars as part of the receptor structure, giving it a narrower specificity than Con A. An ?-linked fucose residue attached to the N-acetylchitobiose portion of the core oligosaccharide significantly enhances affinity. By exploiting this narrower specificity, glycoproteins and glycopeptides can be subfractionated with LCA after initial isolation with Con A.

Purification:
Affinity Purified
Research Area:
Glycobiology
Shipping Conditions:
Ambient
Storage Conditions:
2-8 [o]C
Supplier:
Vector Laboratories
Size:
1mg
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