Description
- SKU:
- PT-092
- Extra Details:
- Peptoids are peptide-mimicking poly-N-substituted glycines, which exhibit enhanced physiological stability and are known to have qualities. They have recently been shown to have activity against Leishmania mexicana axenic amastigotes. Nae is the N-substituted amino ethyl peptoid monomer and Nspe is the (S)-(N-1-phenylethyl)glycine peptoid monomer
- Molecular Weight:
- 1707.1
- Purity:
- >90% by HPLC
- References:
Chongsiriwatana et al (2008) Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides. Proc. Natl. Acad. Sci 105(8) 2794 DOI: 10.1073/pnas.0708254105
Zuckermann (2011) Peptoid origins. Biopolymers, 96 545 doi:10.1002/bip.21573
Sun and Zuckermann (2013) Peptoid Polymers: A Highly Designable Bioinspired Material. ACS Nano 7(6) 4715 https://doi.org/10.1021/nn4015714
Huang et al (2014) Learning from Host-Defense Peptides: Cationic, Amphipathic Peptoids with Potent Anticancer Activity. PLoS ONE 9(2) e90397. https://doi.org/10.1371/journal.pone.0090397
Eggimann et al (2015) Investigating the Anti-leishmanial Effects of Linear Peptoids. ChemMedChem. 10 233 doi:10.1002/cmdc.201402416
- Sequence:
- Nae-Nspe-Nspe-Nae-Nspe-Nspe-Nae-Nspe-Nspe-Nae-Nspe-Nspe-NH2
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Supplier:
- Isca Biochemicals
- Formula:
- C96H123N17O12
- Solubility:
- Soluble in dilute acid