Description
- SKU:
- CG-010
- Additional Names:
- ?-CGRP (human)
- CAS Number:
- 90954-53-3
- Extra Details:
- ?-Calcitonin gene related peptide (human) is a potent, long-lasting vasodilator which possesses protective mechanisms for physiological and pathological conditions involving the cardiovascular system and wound healing. CGRP is primarily released from sensory nerves and can function in the transmission of nociception. ?-Calcitonin gene related peptide (human) acts as an appetite suppressant and contributes to gastric acid secretion.
- Molecular Weight:
- 3789.33
- Purity:
- >95% by hplc
- References:
Brain et al (1985) Calcitonin gene-related peptide is a potent vasodilator. Nature 313 54 PMID: 3917554
Poyner et al (2002) International union of pharmacology XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors. Pharmacol.Revs. 54 233 PMID: 12037140
Russell et al (2014) Calcitonin gene-related peptide: physiology and pathophysiology. Physiol Rev. 94(4) 1099 PMID: 25287861
- Sequence:
- H-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2, disulfide bridge between cysteines 2 and 7
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store dessicated, frozen and in the dark
- Supplier:
- Isca Biochemicals
- Formula:
- C163H267N51O49S2
- Solubility:
- Soluble to 0.50 mg/ml in water
